Package: hilbertSimilarity Type: Package Title: Hilbert Similarity Index for High Dimensional Data Version: 0.4.4.9000 Date: 2026-01-05 Authors@R: c(person('Yann','Abraham',email='yann.abraham@gmail.com',role=c('aut','cre')), person('Marilisa','Neri',email='marilisa.neri@gmail.com',role='aut'), person('John','Skilling',role='ctb')) Description: Quantifying similarity between high-dimensional single cell samples is challenging, and usually requires some simplifying hypothesis to be made. By transforming the high dimensional space into a high dimensional grid, the number of cells in each sub-space of the grid is characteristic of a given sample. Using a Hilbert curve each sample can be visualized as a simple density plot, and the distance between samples can be calculated from the distribution of cells using the Jensen-Shannon distance. Bins that correspond to significant differences between samples can identified using a simple bootstrap procedure. LinkingTo: Rcpp Imports: Rcpp, entropy Suggests: knitr, rmarkdown, ggplot2, dplyr, tidyr, reshape2, bodenmiller, abind License: GPL (>= 3) Encoding: UTF-8 URL: https://github.com/yannabraham/hilbertSimilarity BugReports: https://github.com/yannabraham/hilbertSimilarity/issues VignetteBuilder: knitr RoxygenNote: 7.3.2 Repository: https://yannabraham.r-universe.dev Date/Publication: 2026-01-14 13:30:22 UTC RemoteUrl: https://github.com/yannabraham/hilbertsimilarity RemoteRef: HEAD RemoteSha: 295dff6dc0c3177fa293262f0439b3c9e1a3d5a0 NeedsCompilation: yes Packaged: 2026-06-13 08:15:09 UTC; root Author: Yann Abraham [aut, cre], Marilisa Neri [aut], John Skilling [ctb] Maintainer: Yann Abraham